In "Quantico" (2015-2018), a TV series where Priyanka played the lead role of Alex Parrish, her character's romantic relationships were a significant part of the storyline. Her character's on-again, off-again relationship with her co-star, Ryan McPartlin, was a central plot point.

In terms of romantic storylines in her films, Priyanka has portrayed a wide range of characters. In "Fashion" (2008), she played the role of Mrunalini, a supermodel struggling with her personal and professional life. Her character's tumultuous relationship with her co-star, Abhishek Bachchan, was a significant part of the film.

In 2010, Priyanka began dating her co-star from the film "7 Khoon Maaf," Neil Nitin Mukesh. The relationship, however, ended in 2011.

In "Mary Kom" (2014), Priyanka played the role of a boxer, Mary Kom, who balances her personal life with her career. Her character's relationship with her husband, Onler Laisram, was portrayed as supportive and loving.